Track Product Development

Investigating the Life Sciences

The key for successful decision making is an up-to-date and timely access to relevant knowledge bases of rapidly evolving technological domains.

Valuable knowledge bases are:
  • Full-fledged: retrieve data from a variety of heterogeneous sources to assure extensive coverage of essential information
  • Integrated: merge information in a structured way to track recent developments in any field of interest
A Target Monitoring Report leverages ATA exclusive data acquisition and integration technology and competences to provide thorough characterization of biological targets (e.g. serotonine uptake inhibitors, CB1 agonists), therapeutic areas (e.g. obesity, anxiety; post-traumatic stress disorders), or company R&D portfolios.
 
   
   
   
     
As shown in our Case Study on Coverage & Content, databases differ widely both in terms of coverage and content. Implications are twofold:
  1. A broad database coverage is mandatory: some records can be found in a single data source.
  2. It is essential to apply a rapid and effective procedure to identify and remove redundant information and assemble relevant non-duplicated pieces of information: the same compounds in different databases can be indicated with different names, indications, project leaders, partners, histories, news...

ATA Approach to Information Pooling

  1. Standardize: Uniform names are assigned to companies, indications and mechanisms of action, chemical substances, based on a common vocabulary.
  2. Match: The same fields across different DBs are assigned a coefficient of similarity.
  3. Identify Duplicates: A weighted sum of fields’ similarity measures is used to compute a similarity matrix across records.
  4. Choose Tolerance and Merge: A threshold is fixed for type 1 (merge different projects) and type 2 (duplicate the same project) errors, and unduplicated information from different DBs are merged.
  5. Check Results: In the last phase, ATA personnel check results, taking care of conflicting information, projects with a 50% similarity coefficient and so on.
Constant interaction between analysts and software engineers allows continuous improvements to the automated procedure and a reduction of the human work. The more the procedure is automated, the faster and cheaper is the whole process.

Overview of the Product

A Target Monitoring Report allows our clients to track the "state of the art" in any field of interest. All the features of the biopharmaceutical innovation process are reviewed.

Patents

A Target Monitoring Report depicts the evolution of the number of patents applied for over time, by year of application of the patent. The most active companies in the field are identified.

Granted patents and applications in major patenting offices are included in ATAdb.
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Evolution of the research effort in a selected field over time, as measured by the number of patent families applied for by the most active companies.

R&D Projects

Two examples of the maps and charts provided in the R&D project section of the Target Monitoring Reports.
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For each R&D project started in the selected field, the highest development status is identified. Maps can be sorted on the basis of originating company (and licensees, if any), mechanism of action, therapeutic indication.
Patent information can be tracked for a subset of projects.
The evolution of the R&D projects is graphically represented from the issue of the patent (if any) or preclinical, trough the latest stage reached by the project.
Customized charts can be provided in order to summarize information based on clients’ preferences and decision support systems.

Deals

The analysis of the collaborative agreements among firms in the selected domain allows to identify the transfer of technological capabilities among firms and to identify potential partners.
Information are provided about the object of the deal, financial terms (when publicly disclosed), stage at signing, and therapeutic area.
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Up-to-date information about the deal activities going on in the Life Science Industry in a selected domain.

Publication/Patent Networks

Example of author-author network in a selected domain. The most important researchers are highlighted, and it is possible to distinguish the different research teams working in the field.
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DyNet, ATA’s software technology, is employed to produce network representations, such as linkages among authors in the publications related to the selected domain.

The star scientist are identified through network representations and a summary statistics provided both in terms of number of publications and impact factor.

Price Quotation

ATA price quotation per Target Monitoring Report ranges from € 6,000 to € 12,000 depending on target extent and characteristics.

Quarterly updates of the Target Monitoring Reports covering the target of interest are provided free of charge for one year.

ATA will communicate the percentage of the work that is done automatically.

Clients can ask for further manual control and integration above the default accuracy level. Price quotation will be revised accordingly.

50% discount will be applied if Target Monitoring Reports are produced on non-exclusive basis. An additional discount will be applied if more than 10 Target Monitoring Reports are ordered.

Please insert here below your data to receive a price quotation:

   
   
   
   
 
 
       

For further information, please contact us at info@atalab.com

 ATA - Advanced Technology Assessment